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MunkleyLab

Lab News

PhD opportunity: Unlocking the power of glycans to discover new mechanisms regulating stem cell development

PhD opportunity: Unlocking the power of glycans to discover new mechanisms regulating stem cell development

Exciting new PhD studentship project in our lab joint with Dr David Doupe (Durham University) investigating the role of glycans in stem cell development

https://www.findaphd.com/phds/project/unlocking-the-power-of-glycans-to-discover-new-mechanisms-regulating-stem-cell-development/?p182750

Please contact us for more information and/or to discuss the project

From Ideas to Impact: Rewriting the script on aggressive prostate cancer

PhD opportunity: Unlocking the power of glycans to discover new mechanisms regulating stem cell development

 Watch our webinar about our Prostate Cancer UK funded project:

https://www.youtube.com/watch?v=zFsyAyXniFk

and find out more about our project here:  https://prostatecanceruk.org/research/research-we-fund/ria22-st2-012

Our Facilities

Our Facilities

The GlycoScore blood test is now being tested in a clinical trial for prostate cancer diagnosis


Find out more here: https://medtechtomarket.com/latest-news/cancer-detection-test-manufactured-cinical-trials/

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-unlocking-the-tumour-glyco-code-to-transform-the-diagnosis-and-treatment-of-breast-and-prostate-cancer/?p176147 

Please contact us to discuss the project

Sialylation Inhibition Can Partially Revert Acquired Resistance to Enzalutamide in Prostate Cancer Cells

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

August 2024

Our PhD student Emily has published a new paper in Cancers

https://www.mdpi.com/2072-6694/16/17/2953


Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone

PhD opportunity: Unlocking the tumour glyco-code to transform the diagnosis and treatment of breast and prostate cancer

Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

June 2024

We have published a new paper in eBioMedicine

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00198-1/fulltext#fig1


Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

November 2023

We enjoyed welcoming Ian Smith and Ellie from Prostate Cancer UK to our lab at the Centre for Life


Prostate Cancer Research annual scientist away day London 2023

Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

Targeting aberrant sialylation and fucosylation in prostate cancer cells using potent metabolic inhibitors

November 2023

Kirsty and Maggie represented our lab at this event for networking, collaboration, and training


Targeting aberrant sialylation and fucosylation in prostate cancer cells using potent metabolic inhibitors

Kildare Trust lab visit for an update on our project 'developing new sugar targeting drugs to treat prostate cancer'

Targeting aberrant sialylation and fucosylation in prostate cancer cells using potent metabolic inhibitors

November 2023

We have published a new paper in Glycobiology

 Targeting aberrant sialylation and fucosylation in prostate cancer cells using potent metabolic inhibitors - PubMed (nih.gov) 


The role of GCNT1-mediated O‑glycosylation in aggressive prostate cancer

The role of GCNT1-mediated O‑glycosylation in aggressive prostate cancer

October  2023

We have published a new paper in Scientific Reports

https://rdcu.be/dn8nu 


Welcome to our new PhD student Jess Peng

The role of GCNT1-mediated O‑glycosylation in aggressive prostate cancer

September 2023

Jess has joined our group as an MRC DiMeN funded PhD student and will be jointly supervised by Professor Dani Ungar at the University of York


ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression

August 2023

Our paper about ST6GAL1 in prostate cancer has been published in the Journal of Pathology

https://pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6152

Newcastle University researchers believe new blood test could diagnose prostate cancer

April 2023

Research from our lab funded by Prostate Cancer UK was featured on ITV news. Watch the video report here: https://www.itv.com/news/tyne-tees/2023-04-10/could-a-blood-test-diagnose-early-stage-prostate-cancer

New review article published about prostate cancer bone metastasis

March 2023

Our MRC DiMeN DTP PhD student Emily has published a new review article 'Prostate cancer bone metastases biology and clinical management' in Oncology Letters  https://doi.org/10.3892/ol.2023.13749 

Prostate Cancer Research 'Meet The Scientists' day 2023

March 2023

Kirsty, Maggie and Jennifer attended this event in London to discuss our research with prostate cancer patients and supporters of the charity

Prostate Cancer UK North East Hub lab visit

March 2023

We enjoyed welcoming members of the Prostate Cancer UK North East Hub to our lab at the Centre for Life for their annual meeting, an update on our research projects, and a tour of the labs. Thank you everyone for your insightful questions.

Our new Prostate Cancer UK funded research project: Developing new sugar-targeting drugs to personalise prostate cancer treatment

March 2023

We are excited to start a new project in the lab joint with researchers at Imperial, Sheffield & Zaragoza Universities. Find out more here: https://prostatecanceruk.org/research/research-we-fund/ria21-st2-006 

Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

February 2023

Our paper on GALNT7 in prostate cancer has been published in Oncogene 

https://www.nature.com/articles/s41388-023-02604-x

Welcome to our new Research Assistant Maggie

Welcome to our new Research Assistant Maggie

Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

September 2022

After completing her MRes Cancer project in our lab, Maggie has now started work as a Research Assistant

Prostate Cancer Research visit the lab

Prostate Cancer Research lab visit

Welcome to our new Research Assistant Maggie

Prostate Cancer UK North East Hub lab visit

June 2022

Prostate Cancer Research visited our lab for updates on our project. Find out more about the project they fund: https://www.prostate-cancer-research.org.uk/project/clipping-prostate-cancers-wings/

Prostate Cancer UK North East Hub lab visit

Welcome to our new Research Assistant Maggie

Prostate Cancer UK North East Hub lab visit

May 2022

Members of the Prostate Cancer UK North East Hub visited us for a tour of the lab and updates on our research

International Women's Day 2022

March 2022

Prostate Cancer UK spent a day with us for IWD2022. Find out more: https://twitter.com/prostateuk/status/1501230121101201408

The Panel 2022

March 2022

Jennifer travelled to London to take part in a Prostate Cancer UK panel event discussing the early diagnosis of prostate cancer

Meet the Scientists event

Thank you to the Bob Willis Fund

March 2022

Jennifer, Kirsty and Ning took part in Prostate Cancer Research's Meet the Scientists Day

Thank you to the Bob Willis Fund

Thank you to the Bob Willis Fund

December 2021

Thank you to the Bob Willis fund for supporting our research

https://bobwillisfund.org/news/the-impact-of-your-money-part-1-prostate-cancer-uk

Charity Soul donation

July 2021

Thank you to Charity Soul for visiting us at Newcastle University Cancer and for your very generous donation towards our research

Research under lockdown

January 2021

Find out how we kept our research going while our lab was closed: https://prostatecanceruk.org/about-us/news-and-views/2021/1/dr-jennifer-munkley-research-under-lockdown


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